منابع مشابه
Bone microarchitecture in hemodialysis patients assessed by HR-pQCT.
BACKGROUND AND OBJECTIVES Dialysis patients are at high risk for low-trauma bone fracture. Bone density measurements using dual-energy x-ray absorptiometry (DXA) do not reliably differentiate between patients with and without fractures. The aim of this study was to identify differences in bone microarchitecture between patients with and without a history of fracture using high-resolution periph...
متن کاملLeast-detectable and age-related local in vivo bone remodelling assessed by time-lapse HR-pQCT
We previously developed an image analysis approach for the determination of local sites of bone remodelling using time-lapse in vivo HR-pQCT. The involved image filtering for removing noise was chosen rather aggressively, and also removed some effects of the bone remodelling. In this paper, we quantify these filtering settings using ex vivo reproducibility HR-pQCT images, and determine the leas...
متن کاملBone structural changes after gastric bypass surgery evaluated by HR-pQCT: a two-year longitudinal study
OBJECTIVE, DESIGN AND METHODS Roux-en-Y gastric bypass (RYGB) has proved successful in attaining sustained weight loss but may lead to metabolic bone disease. To assess impact on bone mass and structure, we measured a real bone mineral density at the hip and spine by dual-energy X-ray absorptiometry, and volumetric BMD (vBMD) and bone microarchitecture at the distal radius and tibia by high-res...
متن کاملHas nanomedicine lived up to its promise?
Nanomedicine for diagnosis and treatment of disease, as a discipline has been around for several years, with the first nanotherapeutic product being approved in 1995. Worldwide its importance was recognized with the setting up of several nanomedicine centres in 2004-2006. Many of these centres were set up to accelerate the speed of translation of the research. In this article we review, with a ...
متن کاملIn vivo precision of three HR-pQCT-derived finite element models of the distal radius and tibia in postmenopausal women
BACKGROUND The distal radius is the most common osteoporotic fracture site occurring in postmenopausal women. Finite element (FE) modeling is a non-invasive mathematical technique that can estimate bone strength using inputted geometry/micro-architecture and tissue material properties from computed tomographic images. Our first objective was to define and compare in vivo precision errors for th...
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ژورنال
عنوان ژورنال: Nature Reviews Rheumatology
سال: 2015
ISSN: 1759-4790,1759-4804
DOI: 10.1038/nrrheum.2014.145-c2